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Article

Cooperation-based sperm clusters mediate sperm oviduct entry and fertilization

1 Mar 2021

Abstract excerpt

Sperm cooperation has been observed in multiple species (Pizzari and Foster, 2008), yet its existence and benefit for reproductive success in mammals remains underexplored. Here, combining tissue-clearing with deep three-dimensional (3D) imaging, we demonstrate that postcopulatory mouse sperm congregate into unidirectional sperm cooperative clusters at the utero-tubal junction (UTJ), a key physical barrier for...

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PMID: 33649997
DOI: 10.1007/s13238-021-00825-y

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