Article

Thrombospondin 2 is a key determinant of fibrogenesis in NAFLD

2023-06-02

Abstract excerpt

Hepatic overexpression of the thrombospondin 2 gene (THBS2) and elevated levels of circulating thrombospondin 2 (TSP2) have been observed in patients with chronic liver disease. The current study aimed to identify the specific cells expressing THBS2/TSP2 in non-alcoholic fatty liver disease (NAFLD) and investigate the underlying mechanism behind THBS2/TSP2 up-regulation. Comprehensive NAFLD liver gene datasets, in...

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Literature Corpus work: 4f6a2383-dcb5-5f00-a4ef-caccc2b8bcc0
DOI: 10.1101/2023.06.01.543250

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