Article

Explore the alterations of downstream molecular pathways caused by ARID1A mutation/knockout in human endometrial cancer cells

2023-06-22

Abstract excerpt

<h4>Purpose: </h4> As one of the most common gynecologic malignancies, endometrial cancer (EC) is driven by multiple genetic alterations that may be targeted for treatments. AT-rich interaction domain 1A (ARID1A) gene mutations were reported as early events in endometrial carcinogenesis. Methods To explore the alterations of downstream molecular pathways caused by ARID1A mutations and the associated therapeutic i...

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Literature Corpus work: 4f5696b8-dafb-544c-8654-ca247f93d2be
DOI: 10.21203/rs.3.rs-3066078/v1

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