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Article

ARID1A in Gynecologic Precancers and Cancers.

Reproductive sciences (Thousand Oaks, Calif.) - 1 Aug 2024

Morgan Jaida E, Jaferi Nishah, Shonibare Zainab, Huang Gloria S

Abstract excerpt

The highest frequency of genetic alterations in the tumor suppressor ARID1A occurs in malignancies of the female reproductive tract. The prevalence of ARID1A alterations in gynecologic precancers and cancers is summarized from the literature, and the putative mechanisms of tumor suppressive action examined both in benign/precursor lesions including endometriosis and atypical hyperplasia and in malignancies of the...

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PMID: 38740655
DOI: 10.1007/s43032-024-01585-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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