Article

HSF2 protects against proteotoxicity by maintaining cell-cell adhesion

2018-12-27

Abstract excerpt

<h4>ABSTRACT</h4> Cellular ability to maintain proper protein homeostasis (proteostasis) is essential for survival upon protein-damaging conditions. Heat shock transcription factor 2 (HSF2) is one of the human HSFs activated in response to proteotoxic stress. HSF2 is dispensable for cell survival during acute heat stress, but its amount and DNA-binding activity increase under prolonged proteotoxic stress conditio...

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Literature Corpus work: 4f45ab3b-550d-5191-9b9d-b26023d46dae
DOI: 10.1101/506881

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