Article

Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors

2017-12-03

Abstract excerpt

<h4>ABSTRACT</h4> In malignant transformation, cellular stress response pathways are dynamically mobilized to counterbalance oncogenic activity, keeping cancer cells viable. Therapeutic disruption of this riskily balanced homeostasis might change the outcome of many human cancers, particularly those for which no effective therapy is available. Here, we report the use of Fibroblast Growth Factor 2 (FGF2) to demons...

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Literature Corpus work: 4f40f600-be58-5fc4-8579-20b159dfb8c8
DOI: 10.1101/227496

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