Article

Querying functional drivers in primary murine naïve and memory T cells using RNP-mediated CRISPR-Cas9 Gene Deletion

2026-02-05

Abstract excerpt

<h4>ABSTRACT</h4> Cytotoxic CD8 T lymphocytes (CTL) are critical for the clearance of pathogenic cells via antigen-dependent cell lysis, thus providing protection against infectious diseases and cancers. CTLs represent one of the key targets of immunotherapies and vaccine design. While microarray and single-cell RNA sequencing of effector and memory CD8 T cells have identified several promising gene targets that...

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Literature Corpus work: 4f08b22e-fe4a-5f7d-a0f4-7265e7fe3272
DOI: 10.64898/2026.02.05.704062

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