Article

The Agonist of JWA Gene JAC1 Suppresses Proliferation of Breast Cancer Through the JWA/p38/SMURF1/HER2 Signaling

2020-06-26

Abstract excerpt

<h4>Background: </h4> The overexpression of HER2 is associated with malignant proliferation and invasiveness in breast cancer. Although HER2-targeting drugs have been clinically applied for cancer treatment, none of them could reduce overexpressed HER2. In this study, we reported that JAC1 could suppress proliferation of breast cancer cells via degrading HER2. Methods JWA-HER2 association was analyzed by IHC in 9...

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Literature Corpus work: 4ef27980-cca1-5c12-a916-f70f82bb9967
DOI: 10.21203/rs.3.rs-37842/v1

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