Article

The agonist of JWA gene JAC1 suppresses proliferation of breast cancer through JWA/p38/SMURF1/HER2 signaling

2020-03-05

Abstract excerpt

<h4>Background: </h4> The HER2-positive breast cancer accounts for 20-30% of all breast cancers. The overexpression of HER2 is associated with malignant proliferation and invasiveness in several cancers. Some HER2 targeting drugs are widely used in clinic to block HER2 or its tyrosine kinase and improve the prognosis of patients. However, drug resistance and side effects are still a big challenge worldwide. Our pr...

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Literature Corpus work: 978eafa5-06d8-5103-9e5f-616adf5c8b50
DOI: 10.21203/rs.3.rs-16181/v1

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