Article
MYSM1 co-activates ERα action via histone and non-histone deubiquitination to confer antiestrogen resistance in breast cancer
2022-12-24
Abstract excerpt
Endocrine resistance is a crucial challenge in estrogen receptor alpha (ERα)-positive breast cancer (BCa) therapy. Aberrant alteration in modulation of E2/ERα signaling pathway has emerged as the putative contributor for endocrine resistance in BCa. Thus, identification the efficient ERα cofactor remains necessary for finding a potential therapeutic target for endocrine resistance. Herein, we have demonstrated tha...
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Identifiers and source
- Literature Corpus work
- 2a8b9c60-eb59-52fd-a14b-adf82fc121ef
- DOI
- 10.1101/2022.12.23.521780
