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MYSM1 co-activates ERα action via histone and non-histone deubiquitination to confer antiestrogen resistance in breast cancer

2022-12-24

Abstract excerpt

Endocrine resistance is a crucial challenge in estrogen receptor alpha (ERα)-positive breast cancer (BCa) therapy. Aberrant alteration in modulation of E2/ERα signaling pathway has emerged as the putative contributor for endocrine resistance in BCa. Thus, identification the efficient ERα cofactor remains necessary for finding a potential therapeutic target for endocrine resistance. Herein, we have demonstrated tha...

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Literature Corpus work
2a8b9c60-eb59-52fd-a14b-adf82fc121ef
DOI
10.1101/2022.12.23.521780
Open publication

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MYSM1 co-activates ERα action via histone and non-histone deubiquitination to confer antiestrogen resistance in breast cancerDOI 10.1101/2022.12.23.521780
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