Article

Targeting host glycolysis as a strategy for antimalarial development

2020-10-10

Abstract excerpt

<h4>ABSTRACT</h4> Glycolysis controls cellular energy, redox balance, and biosynthesis. Antiglycolytic therapies are under investigation for treatment of obesity, cancer, aging, autoimmunity, and microbial diseases. Interrupting glycolysis is highly valued as a therapeutic strategy, because glycolytic disruption is generally tolerated in mammals. Unfortunately, anemia is a known dose-limiting side effect of these...

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Literature Corpus work: 4ee9d407-3c3e-565a-8d6f-ef32e1231bff
DOI: 10.1101/2020.10.09.331728

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