Article

<i>Plasmodium falciparum</i> growth is regulated by Sphingosine 1 phosphate produced by Host Erythrocyte Membrane Sphingosine kinase 1

2019-09-03

Abstract excerpt

Sphingosine-1-phosphate (S1P) a bioactive lipid is produced in its primary reservoir, erythrocytes by an enzyme Sphingosine kinase-1 (SphK-1). The activation of such kinases and the subsequent S1P generation and secretion in the blood serum represent a major regulator of many cellular signaling cascades. Orthologue of sphingosine kinases 1 and 2 (SphK-1 and 2) that catalyze the phosphorylation of sphingosine gener...

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Literature Corpus work: acdd0bdd-2493-5c8f-ae5b-2cdb9d9f3fe6
DOI: 10.1101/756502

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