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Persistence of CD8+ skin-resident memory T cells in mice requires TCR signaling

2025-01-10

Abstract excerpt

<h4>Background: </h4> Epidermal-resident memory CD8 + T (T RM ) cells play a significant role in fighting off pathogens. However, CD8 + T RM cells are also central in the pathogenesis of a variety of inflammatory skin diseases. It is unclear whether the generation and persistence of CD8 + T RM cells are dependent on the presence of cognate antigen and T cell receptor (TCR) signaling. <h4>Methods: </h4>: We...

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Literature Corpus work
4ede334c-a159-545e-814e-ba8e14b4751e
DOI
10.22541/au.173652866.63708399/v1
Open publication

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Persistence of CD8+ skin-resident memory T cells in mice requires TCR signalingDOI 10.22541/au.173652866.63708399/v1
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