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Article

The vast majority of CLA+ T cells are resident in normal skin.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2006

Clark Rachael A, Chong Benjamin, Mirchandani Nina, Brinster Nooshin K, Yamanaka Kei-Ichi, Dowgiert Rebecca K, Kupper Thomas S

Abstract excerpt

There are T cells within normal, noninflamed skin that most likely conduct immunosurveillance and are implicated in the development of psoriasis. We isolated T cells from normal human skin using both established and novel methods. Skin resident T cells expressed high levels of CLA, CCR4, and CCR6...

Read the complete abstract on PubMed

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Share to Antigens, Differentiation, T-Lymphocyte
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Membrane Glycoproteins

Share to Receptors, Antigen, T-Cell

Source

Identifiers

PMID: 16547281
DOI: 10.4049/jimmunol.176.7.4431

Genes

CCR4
CCR6
CCR8
CXCR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16547281-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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