Article

A fluorescent l-2-hydroxyglutarate biosensor

2020-07-07

Abstract excerpt

l -2-Hydroxyglutarate ( l -2-HG) plays important roles in diverse physiological processes, such as carbon starvation response, tumorigenesis, and hypoxic adaptation. Despite its importance and intensively studied metabolism, regulation of l -2-HG metabolism remains poorly understood and a regulator specifically responded to l -2-HG has never been identified. Based on the genomic neighborhood analysis of the gen...

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Literature Corpus work: 4ec48db3-acde-5d4a-8a51-fc39383d0327
DOI: 10.1101/2020.07.07.187567

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