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Article

Glyoxal detoxification in Escherichia coli K-12 by NADPH dependent aldo-keto reductases.

Journal of microbiology (Seoul, Korea) - 1 Aug 2013

Lee Changhan, Kim Insook, Park Chankyu

Abstract excerpt

Glyoxal (GO) and methylglyoxal (MG) are reactive carbonyl compounds that are accumulated in vivo through various pathways. They are presumably detoxified through multiple pathways including glutathione (GSH)-dependent/independent glyoxalase systems and NAD(P)H dependent reductases. Previously, we reported an involvement of aldo-ketoreductases (AKRs) in MG detoxification. Here, we investigated the role of various...

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PMID: 23990306
DOI: 10.1007/s12275-013-3087-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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