Article

Immune microenvironment subtypes and association with tumor cell mutations and antigen expression in follicular lymphoma

2021-04-28

Abstract excerpt

Follicular lymphoma (FL) is a B-cell lymphoma with a complex tumor microenvironment that is rich in non-malignant immune cells. We applied single-cell RNA-sequencing to characterize the diverse tumor and immune cell populations of FL and identified major phenotypic subsets of FL T-cells including a novel cytotoxic CD4 T-cell population. Their relative proportions of T-cells defined four major FL subtypes, characte...

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Identifiers and source

Literature Corpus work: 4ebbdb71-05c4-507e-850e-3e19169a4f92
DOI: 10.1101/2021.04.27.441656

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