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Article

Influence of N6-methyladenosine (m6A) modification on cell phenotype in Alzheimer's disease.

PloS one - 1 Jan 2023

Ni Pengyun, Pan Kaiting, Zhao Bingbing

Abstract excerpt

OBJECTIVE: Recent research has suggested that m6A modification takes on critical significance to Neurodegeneration. As indicated by the genome-wide map of m6A mRNA, genes in Alzheimer's disease model achieved significant m6A methylation. This study aimed to investigate the hub gene and pathway of m6A modification in the pathogenesis of AD. Moreover, possible brain regions with higher gene expression levels and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37549144
DOI: 10.1371/journal.pone.0289068
PMCID: PMC10406241

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