Article

Cfap300 regulates the transdifferentiation of Corpuscle of Stannius cells in zebrafish

2025-10-06

Abstract excerpt

Stanniocalcin 1 (Stc1) is a hormone secreted by the Corpuscle of Stannius (CS) gland in teleost fish, including zebrafish, where it regulates calcium homeostasis. The CS gland forms by transdifferentiation of pronephric tubule epithelial cells at the distal early (DE) and distal late (DL) boundary. Although transdifferentiation is known in development and disease, the underlying mechanisms remain unclear. Here, we...

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Literature Corpus work: 4e4d57a6-b8c0-54a3-8687-e02430ad8538
DOI: 10.1101/2025.10.06.680176

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