Article

HIV skews the SARS-CoV-2 B cell response toward an extrafollicular maturation pathway

2022-06-15

Abstract excerpt

<h4>Background</h4> HIV infection dysregulates the B cell compartment, affecting memory B cell formation and the antibody response to infection and vaccination. Understanding the B cell response to SARS-CoV-2 in people living with HIV (PLWH) may explain the increased morbidity, reduced vaccine efficacy, reduced clearance, and intra-host evolution of SARS-CoV-2 observed in some HIV-1 coinfections. <h4>Methods</h4>...

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Literature Corpus work: 4e45edcd-4209-51e7-b972-1cc1fb3ec05e
DOI: 10.1101/2022.06.14.496062

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