Article

BAFF-R and CD21 dysregulation inhibits memory B cell persistence in patients with common variable immunodeficiency

2025-05-21

Abstract excerpt

<h4>Structured Abstract</h4> <h4>Background</h4> Individuals with common variable immunodeficiency (CVID) are at increased risk of respiratory infections such as SARS-CoV-2 infection due to poorly understood defects within the memory B cell (MBC) compartment. The COVID-19 pandemic presented a unique opportunity to investigate the effects of a novel pathogen and vaccination on the immune system of patients with CVI...

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Literature Corpus work: 8ab29e14-2ee4-52b4-b95a-38d8b419aa2e
DOI: 10.1101/2025.05.20.25327919

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