Article

Highly sensitive in situ proteomics with cleavable fluorescent tyramide reveals human neuronal heterogeneity

2019-02-08

Abstract excerpt

<h4>ABSTRACT</h4> The ability to comprehensively profile proteins in intact tissues in situ is crucial for our understanding of health and disease. However, the existing methods suffer from low sensitivity and limited sample throughput. To address these issues, here we present a highly sensitive and multiplexed in situ protein analysis approach using cleavable fluorescent tyramide and off-the-shelf antibodies. Co...

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Literature Corpus work: 4e44843e-669a-5ddf-929c-46ddbafe0c18
DOI: 10.1101/539106

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