Article

Gonococcal aggregation causes upregulation of genes involved in antibiotic tolerance

2025-01-18

Abstract excerpt

Aggregation and biofilm formation can increase the tolerance of bacteria to external stressors, including antibiotic treatment. While resistant bacteria grow at an elevated drug dose, tolerant bacteria survive longer-term treatment. The mechanisms by which aggregation confers tolerance are insufficiently characterized for most organisms, including the human pathogen Neisseria gonorrhoeae . We hypothesize that bac...

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Literature Corpus work: 4e430a4c-949c-5df7-b7e9-aaa4040cb1f8
DOI: 10.1101/2025.01.17.633513

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