Article

Multi-Scale Geometric Network Analysis Identifies Melanoma Immunotherapy Response Gene Modules

2023-11-21

Abstract excerpt

Melanoma response to immune-modulating therapy remains incompletely characterized at the molecular level. In this study, we assess melanoma immunotherapy response using a multi-scale network approach to identify gene modules with coordinated gene expression in response to treatment. Using gene expression data of melanoma before and after treatment with nivolumab, we modeled gene expression changes in a correlation...

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Literature Corpus work: 4e2f1a64-7704-52da-9b54-398614340a95
DOI: 10.1101/2023.11.21.568144

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