Article

A Graph Curvature-Based Pipeline for Discovering Immune Checkpoint Response Biomarkers

2024-09-08

Abstract excerpt

Immune checkpoint inhibitors (ICIs), also called immune checkpoint blockers, are a promising category of targeted therapy for solid tumors. Predicting which patients will respond to ICI therapy remains an open problem under active investigation. This paper adds to this effort by developing a modular pipeline for the discovery of biomarkers from tumor RNA-sequencing data. We contextualize gene expression measuremen...

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Identifiers and source

Literature Corpus work: 8c700684-f88d-51a8-ba24-1afd27598fb9
DOI: 10.1101/2024.09.04.611306

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