Article

Minute- and second-scale hippocampal network dysfunctions in the 3xTgAD mouse model of Alzheimer’s disease are prevented by TSPO knockout

2025-11-12

Abstract excerpt

The 18kDa translocator protein (TSPO) is widely recognized as a biomarker of neuroinflammation, but recent evidence suggests that it may also play a direct role in the pathophysiology of neurological conditions with an inflammatory component such as Alzheimer’s disease (AD). In this study, we leveraged functional ultrasound imaging (fUSi) to assess how TSPO knockout influences brain activity and connectivity in th...

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Literature Corpus work: 4e100d2b-5fe0-5291-a49e-1396a735093e
DOI: 10.1101/2025.11.11.687784

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Minute- and second-scale hippocampal network dysfunctions in the 3xTgAD mouse model of Alzheimer’s disease are prevented by TSPO knockoutDOI 10.1101/2025.11.11.687784Read

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