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Transcriptomic and glucose metabolism of connectome dynamics variability in temporal lobe epilepsy revealed by simultaneous PET-fMRI

19 May 2025

Abstract excerpt

Temporal lobe epilepsy (TLE) is associated to genetic predisposition, metabolic abnormalities, and disruptions in brain connectivity. However, the relationships between genetic factors, metabolic processes, and brain network dynamics are not yet fully understood. Simultaneous positron emission tomography and function magnetic resonance imaging (PET/fMRI) data were collected from 66 patients with TLE and 38...

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PMID: 40398518
DOI: 10.1016/j.nbd.2025.106967

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