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Nuclear size and physical properties of the nucleoplasm are determined by colloid osmotic pressure at the nuclear envelope

2026-07-23

Abstract excerpt

The size of the nucleus scales with cell size, suggesting a universal scaling rule. Yet the biophysical determinants of nuclear size and the significance and consequences of altered nuclear-to-cell (N/C) ratios, which are observed across diverse pathological states and cell-fate transitions, remain poorly understood. Recent theoretical models propose that nuclear size arises from a balance of colloid osmotic press...

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Literature Corpus work
4de83d2b-24dc-535d-8c10-e231e5fe0aee
DOI
10.64898/2026.07.21.739918
Open publication

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Nuclear size and physical properties of the nucleoplasm are determined by colloid osmotic pressure at the nuclear envelopeDOI 10.64898/2026.07.21.739918
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