Article

The perinuclear ER scales nuclear size independently of cell size in early embryos

2019-10-25

Abstract excerpt

<h4>SUMMARY</h4> Nuclear size plays pivotal roles in gene expression, embryo development, and disease. A central hypothesis in organisms ranging from yeast to vertebrates is that nuclear size scales to cell size. This implies that nuclei may reach steady state sizes set by limiting cytoplasmic pools of size-regulating components. By monitoring nuclear dynamics in early sea urchin embryos, we found that nuclei und...

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Literature Corpus work: 7afd922e-34ad-5ace-8840-c6c35f9b17a9
DOI: 10.1101/818724

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