Article

Covering All Bases: A Computational Method to Design Broad-spectrum T-cell-inducing Vaccines Applied to <i>Betacoronaviruses</i>

2025-04-15

Abstract excerpt

Antigenically diverse pathogens, such as coronaviruses, pose substantial threats to global health. This highlights the need for effective broad-spectrum vaccines that elicit robust immune responses in a large proportion of the human population against a wide array of pathogen variants. Here, we introduce Spectravax, an AI-enabled computational method to design broad-spectrum vaccines that account for genetic diver...

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Literature Corpus work: 4dd1bb7d-a95e-51e3-bcc3-0c0ac050a992
DOI: 10.1101/2025.04.14.648815

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