Back to search

Article

The Wiskott-Aldrich Syndrome: The Actin Cytoskeleton and Immune Cell Function

2010-01-01

Abstract excerpt

Wiskott-Aldrich syndrome (WAS) is a rare X-linked recessive primary immunodeficiency characterised by immune dysregulation, microthrombocytopaenia, eczema and lymphoid malignancies. Mutations in the WAS gene can lead to distinct syndrome variations which largely, although not exclusively, depend upon the mutation. Premature termination and deletions abrogate Wiskott-Aldrich syndrome protein (WASp) expression and l...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4d3a3a30-6e61-5e21-b3ce-7dacc5a2dbc9
DOI
10.1155/2010/781523
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The Wiskott-Aldrich Syndrome: The Actin Cytoskeleton and Immune Cell FunctionDOI 10.1155/2010/781523
The Wiskott-Aldrich syndrome: The actin cytoskeleton and immune cell function.Semantic proximity
New insights into the biology of Wiskott-Aldrich syndrome (WAS).Semantic proximity
Wiskott-Aldrich syndrome: a comprehensive review.Semantic proximity
Actin cytoskeletal defects in immunodeficiency.Semantic proximity
Clinical spectrum, pathophysiology and treatment of the Wiskott–Aldrich syndromeSemantic proximity
Wiskott-Aldrich Syndrome: a model for defective actin reorganization, cell trafficking and synapse formation.Semantic proximity
The Wiskott–Aldrich syndromeSemantic proximity
Wiskott–Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activationSemantic proximity
The Wiskott-Aldrich syndrome protein (WASP): roles in signaling and cytoskeletal organization.Semantic proximity
The Wiskott-Aldrich syndrome.Semantic proximity
Wiskott‐Aldrich syndrome protein: Emerging mechanisms in immunitySemantic proximity
Recent advances in understanding the pathophysiology of Wiskott-Aldrich syndrome.Semantic proximity
Select a neighboring publication to make it the new centre.