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A New Proposed Approach to Categorize Sepsis Sub-phenotypes Based on Combined Trajectories of Perfusion Index and Central Venous Oxygen Saturation.

Shock (Augusta, Ga.) - 1 Sept 2026

Wang Xinchen, Wang Xiaoting, Kang Yan, Zhou Xiang, Long Yun, Du Wei

Abstract excerpt

BACKGROUND: Circulatory disturbances in sepsis are heterogeneous but may manifest as a mismatch between peripheral perfusion and tissue oxygenation. Peripheral perfusion index (PI) and central venous oxygen saturation (ScvO 2 ) have been independently validated as prognostic markers in sepsis; however, their combined utility remains unexplored. METHODS: This retrospective cohort study included patients admitted...

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Intensive Care Units
Oxygen
Phenotype
Prognosis

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PMID: 41457045
DOI: 10.1097/SHK.0000000000002764
PMCID: PMC13456544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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