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Human alveolar macrophage response to <i>Mycobacterium tuberculosis</i> : immune characteristics underlying large inter-individual variability

2022-03-16

Abstract excerpt

Mycobacterium tuberculosis ( M.tb ) establishes residence and growth in human alveolar macrophages (AMs). Large inter-individual variation in M.tb -AM interactions is a potential early indicator of TB risk and efficacy of therapies and vaccines. Herein, we systematically analyze interactions of a virulent M.tb strain with freshly isolated human AMs from 28 healthy adult donors, measuring host RNA expression and...

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Literature Corpus work
4d21904d-abab-5739-ae2a-c69703c3dd77
DOI
10.1101/2022.03.14.484235
Open publication

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Human alveolar macrophage response to <i>Mycobacterium tuberculosis</i> : immune characteristics underlying large inter-individual variabilityDOI 10.1101/2022.03.14.484235
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