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Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosis

6 Aug 2021

Abstract excerpt

Blood transcriptomics have revealed major characteristics of the immune response in active TB, but the signature early after infection is unknown. In a unique clinically and temporally well-defined cohort of household contacts of active TB patients that progressed to TB, we define minimal changes in gene expression in incipient TB increasing in subclinical and clinical TB. While increasing with time, changes in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34491266
DOI: 10.1084/jem.20210915

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