Article

Toll-like receptor 7 (TLR7)-mediated antiviral response protects mice from lethal SARS-CoV-2 infection

2023-05-09

Abstract excerpt

<h4>ABSTRACT</h4> SARS-CoV-2-induced impaired antiviral and excessive inflammatory responses cause fatal pneumonia. However, the key pattern recognition receptors that elicit effective antiviral and lethal inflammatory responses in-vivo are not well defined. CoVs possess single-stranded RNA (ssRNA) genome that is abundantly produced during infection and stimulates both antiviral interferon (IFN) and inflammatory...

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Literature Corpus work: 4d0e09ac-f0c8-58c1-ad3f-3a013b977890
DOI: 10.1101/2023.05.08.539929

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