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The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication

2024-03-27

Abstract excerpt

<h4>ABSTRACT</h4> SARS-CoV-2 infection leads to vastly divergent clinical outcomes ranging from asymptomatic infection to fatal disease. Co-morbidities, sex, age, host genetics and vaccine status are known to affect disease severity. Yet, how the inflammatory milieu of the lung at the time of SARS-CoV-2 exposure impacts the control of viral replication remains poorly understood. We demonstrate here that immune ev...

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Literature Corpus work
6c9eae28-f972-5f6c-b424-878e28d37335
DOI
10.1101/2024.03.27.586885
Open publication

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The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replicationDOI 10.1101/2024.03.27.586885
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