Article

Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes

2023-04-17

Abstract excerpt

Acute myeloid leukemia (AML) is an aggressive disease with complex and heterogeneous biology. Although several genomic classifications have been proposed, there is a growing interest in going beyond genomics to stratify AML. In this study, we profile the sphingolipid family of bioactive molecules in 213 primary AML samples and 30 common human AML cell lines. Using an integrative approach, we identify two distinct...

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Literature Corpus work: 4cf0373d-3093-5a90-bbd1-94e66ab9cf57
DOI: 10.1101/2023.04.13.536805

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