Article

Label-free morphology-based phenotypic analysis of spinal and bulbar muscular atrophy muscle cell models

2024-10-28

Abstract excerpt

<title>Abstract</title> <p>Background Spinal and bulbar muscular atrophy (SBMA) is a neuromuscular disorder caused by a CAG trinucleotide expansion in the <italic>androgen receptor</italic> (<italic>AR</italic>) gene. The pathogenesis of SBMA is not fully understood and there are less effective treatments for SBMA. To improve the quality of in vitro cell-based assays for the evaluation of potential drug candidat...

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Literature Corpus work: 4ce8aab0-b5de-50bf-9e6c-abcbf2e0b9bb
DOI: 10.21203/rs.3.rs-5322667/v1

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