Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biomarkers of Spinal and Bulbar Muscle Atrophy (SBMA): A Comprehensive Review

10 Oct 2018

Abstract excerpt

Spinal and bulbar muscular atrophy (SBMA), also known as Kennedy's disease, is a rare, X-linked, late onset neuromuscular disorder. The disease is caused by a CAG trinucleotide repeat expansion in the first exon of the androgen receptor gene. It is characterized by slowly progressive lower motor neurons degeneration, primary myopathy and widespread multisystem involvement. Respiratory involvement is rare, and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Neurodegenerative Diseases
Share to Muscle Physiology and Disorders
Share to Neurogenetic and Muscular Disorders Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30364135
DOI: 10.3389/fneur.2018.00844

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biomarkers of Spinal and Bulbar Muscle Atrophy (SBMA): A Comprehensive ReviewPMID 30364135Read ↗

Disease mechanism, biomarker and therapeutics for spinal and bulbar muscular atrophy (SBMA)Semantic proximity Read ↗

Spinal and bulbar muscular atrophy: From molecular pathogenesis to pharmacological intervention targeting skeletal muscleSemantic proximity Read ↗

[Molecular-targeted therapies for spinal and bulbar muscular atrophy].Semantic proximity Read ↗

Kennedy's disease: pathogenesis and clinical approaches.Semantic proximity Read ↗

Molecular Mechanisms and Therapeutics for SBMA/Kennedy's DiseaseSemantic proximity Read ↗

Early pathogenesis of spinal and bulbar muscular atrophy uncovered by human iPSC-derived motor neurons highlights pathogenic neuropeptides as therapeutic targetsSemantic proximity Read ↗

Biomarkers in Motor Neuron Disease: A State of the Art ReviewSemantic proximity Read ↗

Biomarkers in 5q-associated spinal muscular atrophy-a narrative review.Semantic proximity Read ↗

Heterogeneous phenotype and cardiovascular comorbidities in Swedish patients with spinobulbar muscular atrophy.Semantic proximity Read ↗

Beyond motor neurons: expanding the clinical spectrum in Kennedy's disease.Semantic proximity Read ↗

A Systematic Review of the Association between the Age of Onset of Spinal-Bulbar Muscular Atrophy (Kennedy’s Disease) and the Length of CAG Repeats in the Androgen Receptor GeneSemantic proximity Read ↗

Plasma pNfH levels differentiate SBMA from ALSSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.