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Multidimensional MRI reveals cellular-scale microstructural phenotypes in human brain aging

2026-03-31

Abstract excerpt

Brain aging is accompanied by profound cellular and microstructural changes that precede overt tissue loss, yet in vivo MRI studies largely emphasize macroscopic measures or isolated diffusion and relaxation metrics, providing limited insight into how cellular-scale tissue architecture is altered across the adult lifespan. Here, we apply multidimensional diffusion–relaxation MRI (MD-MRI) to map voxel-wise microstr...

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Literature Corpus work
fefac23b-e9a2-5f46-a8ac-4792b59b3145
DOI
10.64898/2026.03.29.715117
Open publication

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Multidimensional MRI reveals cellular-scale microstructural phenotypes in human brain agingDOI 10.64898/2026.03.29.715117
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