Article

Dose- and time-dependent effects of hyaluronidase on structural cells and the extracellular matrix of the skin

2020-05-08

Abstract excerpt

BACKGROUNDHyaluronic acid (hyaluronan; HA) is an essential component of the extracellular matrix (ECM) of the skin. The HA-degrading enzyme hyaluronidase (HYAL) is critically involved in the HA-metabolism. Yet, only little information is available regarding the skin´s HA-HYAL interactions on the molecular and cellular levels.To analyze the dose- and time-dependent molecular and cellular effects of HYAL on structur...

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Literature Corpus work: 4caf4b9d-8b02-56bc-9108-3dff225b3350
DOI: 10.21203/rs.3.rs-26784/v1

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