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Structural characterization and biological properties of degradation byproducts from hyaluronan after acid hydrolysis

2012-05-01

Abstract excerpt

The generation of degradation byproducts from hyaluronan during its acid hydrolysis was studied. The degradation byproducts were removed from reaction mixture by ultrafiltration, followed by ionex separation and purification on a reversed-phase HPLC column. Isolated fractions were structurally analyzed by NMR and mass spectrometry. Results indicated that when acid hydrolysis is performed at 100°C for 24h, about 0....

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Literature Corpus work
27a1ae4c-af6d-52e7-a195-3effa2f69fd4
DOI
10.1016/j.carbpol.2012.02.031
Open publication

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Structural characterization and biological properties of degradation byproducts from hyaluronan after acid hydrolysisDOI 10.1016/j.carbpol.2012.02.031
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