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Article

Hyaluronan Facilitates Transforming Growth Factor-β1-mediated Fibroblast Proliferation

4 Jan 2008

Abstract excerpt

This study aims to understand the role of the matrix polysaccharide hyaluronan (HA) in influencing fibroblast proliferation and thereby affecting wound healing outcomes. To determine mechanisms that underlie scarred versus scar-free healing, patient-matched dermal and oral mucosal fibroblasts were used as models of scarring and non-scarring fibroblast phenotypes. Specifically, differences in HA generation between...

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PMID: 18174158
DOI: 10.1074/jbc.m704819200

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