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KEK-6: A TRUNCATED-TRK-LIKE RECEPTOR FOR <i>DROSOPHILA</i> NEUROTROPHIN 2 REGULATES STRUCTURAL SYNAPTIC PLASTICITY

2017-04-06

Abstract excerpt

<h4>ABSTRACT</h4> Neurotrophism, structural plasticity, learning and long-term memory in mammals critically depend on neurotrophins binding Trk receptors to activate tyrosine kinase (TyrK) signalling, but Drosophila lacks full-length Trks, raising the question of how these processes occur in the fly. Paradoxically, truncated Trk isoforms lacking the TyrK predominate in the adult human brain, but whether they hav...

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Literature Corpus work: 4c86b3f0-e4ce-5d8c-8038-033495b09deb
DOI: 10.1101/124644

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