Article

HIV-DRLink: A tool for detecting linked HIV-1 drug resistance mutations in next generation sequencing data

2019-12-06

Abstract excerpt

The prevalence of HIV-1 drug resistance is increasing worldwide and monitoring its emergence is important for the successful management of populations receiving combination antiretroviral therapy (cART). Using Ultrasensitive Single-Genome Sequencing (uSGS), a next-generation method that avoids PCR bias and PCR recombination, a recent report showed that pre-existing dual-class drug resistance mutations linked on th...

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Literature Corpus work: 4c7aac68-8417-5412-9095-324813139406
DOI: 10.1101/866715

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