Article
Full-spectrum HIV drug resistance mutation detection by high-resolution complete pol gene sequencing.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jul 2023
Faraci Gina, Park Sung Yong, Dubé Michael P, Lee Ha Youn
Abstract excerpt
BACKGROUND: Drug resistance mutation testing is a key element for HIV clinical management, informing effective treatment regimens. However, resistance screening in current clinical practice is limited in reporting linked cross-class resistance mutations and minority variants, both of which may increase the risk of virological failure. METHODS: To address these limitations, we obtained 358 full-length pol gene...
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