Article
Short Communication: HIV-DRLink: A Tool for Reporting Linked HIV-1 Drug Resistance Mutations in Large Single-Genome Data Sets Using the Stanford HIV Database.
AIDS research and human retroviruses - 1 Nov 2020
Shao Wei, Boltz Valerie F, Hattori Junko, Bale Michael J, Maldarelli Frank, Coffin John M, Kearney Mary F
Abstract excerpt
The prevalence of HIV-1 drug resistance is increasing worldwide and monitoring its emergence is important for the successful management of populations receiving combination antiretroviral therapy. It is likely that pre-existing drug resistance mutations linked on the same viral genomes are predictive of treatment failure. Because of the large number of sequences generated by ultrasensitive single-genome...
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