Article
Drug resistance mutations in HIV: new bioinformatics approaches and challenges.
Current opinion in virology - 1 Dec 2021
Blassel Luc, Zhukova Anna, Villabona-Arenas Christian J, Atkins Katherine E, Hué Stéphane, Gascuel Olivier
Abstract excerpt
Drug resistance mutations appear in HIV under treatment pressure. Resistant variants can be transmitted to treatment-naive individuals, which can lead to rapid virological failure and can limit treatment options. Consequently, quantifying the prevalence, emergence and transmission of drug resistance is critical to effectively treating patients and to shape health policies. We review recent bioinformatics...
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