Article

ASCARIS: Positional Feature Annotation and Protein Structure-Based Representation of Single Amino Acid Variations

2022-11-04

Abstract excerpt

<h4>Motivation</h4> Genomic variations may cause deleterious effects on protein functionality and perturb biological processes. Elucidating the effects of variations is critical for developing novel treatment strategies for diseases of genetic origin. Computational approaches have been aiding the work in this field by modeling and analyzing the mutational landscape. However, new approaches are required, especiall...

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Literature Corpus work: 4c54fa36-dedf-5b6a-94bd-eca8683ab1c6
DOI: 10.1101/2022.11.03.514934

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