Article

ΔFOSB in the nucleus accumbens core is required for increased anxiety, but not decreased social motivation, following estrogen withdrawal in female mice

2025-10-22

Abstract excerpt

During pregnancy, estrogen levels rise dramatically, but quickly drop to prepartum levels following birth, and remain suppressed until ovulation resumes. This “postpartum estrogen withdrawal” state has been linked to changes in the brain and behavior in humans and rodents. Previous research has demonstrated that following a hormone-simulated pseudopregnancy (HSP), an experimental model of postpartum estrogen withd...

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Literature Corpus work: 4c446bdb-2248-52cf-a03c-c7e2383b8e0c
DOI: 10.1101/2025.10.21.683778

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